1H-Benzimidazol-2-amine,4-nitro-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazol-2-amine,4-nitro-(9CI)
• CAS No.: 24370-22-7
• Molecular Formula: C₇H₆N₄O₂
• Molecular Weight: 178.15
• Hs Code.: 2933990090
• Mol file: 24370-22-7.mol

Synonyms:1H-Benzimidazol-2-amine,4-nitro- (9CI); Benzimidazole, 2-amino-4-nitro- (8CI);2-Amino-4-nitrobenzimidazole

Chemical Property of 1H-Benzimidazol-2-amine,4-nitro-(9CI)

Chemical Property:

• Boiling Point: 478.5±37.0 °C(Predicted)
• PKA: 8.01±0.30(Predicted)
• PSA: 101.25000
• Density: 1.631±0.06 g/cm3(Predicted)
• LogP: 1.50660

Purity/Quality:

99% ^*data from raw suppliers

4-NITRO-1H-BENZIMIDAZOL-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazol-2-amine,4-nitro-(9CI)

There total 4 articles about 1H-Benzimidazol-2-amine,4-nitro-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-Nitrophenylene-1,2-diamine (99-56-9) → 2-amino-4-nitro-1H-benzimidazole (24370-22-7)

Guidance literature:

With bromocyane; In methanol; water; acetonitrile;

Reference yield: 93.0%

bromocyane (506-68-3) + 4-Nitrophenylene-1,2-diamine (99-56-9) → 2-amino-4-nitro-1H-benzimidazole (24370-22-7)

Guidance literature:

In methanol; water; acetonitrile; at 20 ℃; for 0.333333h;

Reference yield: 55.0%

bromocyane (506-68-3) + 2,3-diamino-nitrobenzene (3694-52-8) → 2-amino-4-nitro-1H-benzimidazole (24370-22-7)

Guidance literature:

In methanol; for 4h; Reflux;

DOI:10.1002/jhet.786

upstream raw materials:

bromocyane

2,3-diamino-nitrobenzene

4-Nitrophenylene-1,2-diamine

Downstream raw materials:

1H-benzo[d]imidazole-2,5-diamine