(4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate

Base Information

• Chemical Name: (4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate
• CAS No.: 1092964-63-0
• Molecular Formula: C₂₀H₂₈O₆
• Molecular Weight: 364.439
• Mol file: 1092964-63-0.mol

Synonyms:(4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate

Chemical Property of (4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate

There total 1 articles about (4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-ol (1092964-62-9) + 4,4-dimethoxybutan-1-oic acid (35848-90-9) → (4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate (1092964-63-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 50h; Inert atmosphere;

DOI:10.1002/anie.200803791

Reference yield: 70.0%

(4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-yl 4,4-dimethoxybutanoate (1092964-63-0) → (4aR,8aS)-6-(3,3-dimethoxypropyl)-4a-methyl-2-phenyl-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin (1092964-64-1)

Guidance literature:

With 1,1-Dibromoethane; N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; lead(II) chloride; zinc; In tetrahydrofuran; dichloromethane; for 1h; Inert atmosphere; Reflux;

DOI:10.1002/anie.200803791

upstream raw materials:

(4S,5R)-4-allyl-5-methyl-2-phenyl-1,3-dioxan-5-ol

4,4-dimethoxybutan-1-oic acid

Downstream raw materials:

(4aR,8aS)-6-(3,3-dimethoxypropyl)-4a-methyl-2-phenyl-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin