(5-nitro-pentane-2-one)-triphenyl-phosporane

Base Information

• Chemical Name: (5-nitro-pentane-2-one)-triphenyl-phosporane
• CAS No.: 166179-39-1
• Molecular Formula: C₂₃H₂₂NO₃P
• Molecular Weight: 391.406
• Mol file: 166179-39-1.mol

Synonyms:(5-nitro-pentane-2-one)-triphenyl-phosporane

Chemical Property of (5-nitro-pentane-2-one)-triphenyl-phosporane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5-nitro-pentane-2-one)-triphenyl-phosporane

There total 3 articles about (5-nitro-pentane-2-one)-triphenyl-phosporane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(5-nitro-pentane-2-one)-triphenyl-phosponium bromide → (5-nitro-pentane-2-one)-triphenyl-phosporane (166179-39-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1016/S0040-4039(00)76859-6

Reference yield:

5-nitro-2-pentanone (22020-87-7) → (5-nitro-pentane-2-one)-triphenyl-phosporane (166179-39-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 55 percent / Br₂ / methanol / 4 h / Ambient temperature

2: 89 percent / benzene / 24 h / Ambient temperature

3: 72 percent / 1 percent NaOH / CH₂Cl₂ / 0.5 h / Ambient temperature

With sodium hydroxide; bromine; In methanol; dichloromethane; benzene;

DOI:10.1016/S0040-4039(00)76859-6

Reference yield:

1-(bromo)-5-(nitro)-pentane-2-one (166179-38-0) → (5-nitro-pentane-2-one)-triphenyl-phosporane (166179-39-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / benzene / 24 h / Ambient temperature

2: 72 percent / 1 percent NaOH / CH₂Cl₂ / 0.5 h / Ambient temperature

With sodium hydroxide; In dichloromethane; benzene;

DOI:10.1016/S0040-4039(00)76859-6

upstream raw materials:

5-nitro-2-pentanone

1-(bromo)-5-(nitro)-pentane-2-one