2-(3-METHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

Base Information

• Chemical Name: 2-(3-METHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE
• CAS No.: 24037-72-7
• Molecular Formula: C₉H₁₁NO₂*ClH
• Molecular Weight: 201.653
• Hs Code.: 2922509090
• Mol file: 24037-72-7.mol

Synonyms:Acetophenone,2-amino-3'-methoxy-, hydrochloride (8CI); Ethanone,2-amino-1-(3-methoxyphenyl)-, hydrochloride (9CI);2-Amino-1-(3-methoxyphenyl)ethanone hydrochloride;2-Amino-3'-methoxyacetophenone hydrochloride

Chemical Property of 2-(3-METHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

Chemical Property:

• Vapor Pressure: 0.000235mmHg at 25°C
• Melting Point: 182-183 °C
• Boiling Point: 320.2°Cat760mmHg
• Flash Point: 147.5°C
• PSA: 52.32000
• Density: g/cm³
• LogP: 2.33890

Purity/Quality:

97% ^*data from raw suppliers

2-amino-1-(3-methoxyphenyl)ethan-1-onehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(3-METHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

There total 4 articles about 2-(3-METHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

→ 2-amino-1-(3-methoxyphenyl)ethan-1-one hydrochloride (24037-72-7)

Guidance literature:

Reference yield: 79.0%

2-bromo-3'-methoxyacetophenone (5000-65-7) → 2-amino-1-(3-methoxyphenyl)ethan-1-one hydrochloride (24037-72-7)

Guidance literature:

2-bromo-3'-methoxyacetophenone; With sodium diformamide; In acetonitrile; at 75 ℃; for 8h;

With hydrogenchloride; In water; for 1h; Reflux;

DOI:10.1002/adsc.202000171

Reference yield: 13.0%

2-azido-1-(3-methoxyphenyl)ethan-1-one (194787-89-8) → 2-amino-1-(3-methoxyphenyl)ethan-1-one hydrochloride (24037-72-7)

Guidance literature:

With hydrogen; 5% Pd-CaCO3; In ethanol; for 6h;

upstream raw materials:

2-azido-1-(3-methoxyphenyl)ethan-1-one

2-azido-1-(4-methoxyphenyl)ethan-1-one

2-bromo-3'-methoxyacetophenone

Downstream raw materials:

tert-butyl [2-amino-2-(3-methoxyphenyl)ethyl]carbamate

tert-butyl (2-(3-methoxyphenyl)-2-oxoethyl)carbamate