(4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone

Base Information Edit

Chemical Name:(4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone
CAS No.:95798-32-6
Molecular Formula:C₂₇H₂₇NO₃S
Molecular Weight:445.582
Hs Code.:
Mol file:95798-32-6.mol

Synonyms:(4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone Edit

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Technology Process of (4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone

There total 2 articles about (4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77943-39-6
4-methyl-5-phenyloxazolidin-2-one

: 95798-32-6
(4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, 2.) 0 deg C, 0.5 h

2: 1.) LDA / 1.) THF, hexane, -78 deg C, 0.5 h, 2.) from -25 deg C to 0 deg C 4 h

With n-butyllithium; lithium diisopropyl amide;
DOI:10.1021/jo00211a008

Reference yield:

: 15960-81-3
benzyl bromomethyl thioether

: 95841-14-8
(4R,5S)-3-(3-phenylpropionyl)-4-methyl-5-phenyl-oxazolidin-2-one

: 95798-32-6
(4R,5S)-3-<(2R)-1-oxo-2-<<(phenylmethyl)thio>methyl>-3-phenylpropyl>-4-methyl-5-phenyl-2-oxazolidinone

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, hexane, -78 deg C, 0.5 h, 2.) from -25 deg C to 0 deg C 4 h;
DOI:10.1021/jo00211a008