1-[2-(2-Acetylphenyl)phenyl]ethanone

Base Information

• Chemical Name: 1-[2-(2-Acetylphenyl)phenyl]ethanone
• CAS No.: 24017-95-6
• Molecular Formula: C16H14 O2
• Molecular Weight: 238.286
• Hs Code.: 2914399090
• DSSTox Substance ID: DTXSID80393265
• Nikkaji Number: J88.222D
• Wikidata: Q82191976
• Mol file: 24017-95-6.mol

Synonyms:2,2'-DIACETYLBIPHENYL;1-[2-(2-acetylphenyl)phenyl]ethanone;24017-95-6;2,2'-diacetyl-biphenyl;SCHEMBL978600;DTXSID80393265;AKOS022506875;FT-0609199;1-(2'-acetyl[1,1'-biphenyl]-2-yl)ethanone;A817042

Chemical Property of 1-[2-(2-Acetylphenyl)phenyl]ethanone

Chemical Property:

• Boiling Point: 408oC at 760 mmHg
• Flash Point: 152.7oC
• PSA: 34.14000
• Density: 1.094g/cm3
• LogP: 3.75880
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 238.099379685
• Heavy Atom Count: 18
• Complexity: 289

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC=CC=C1C2=CC=CC=C2C(=O)C

Technology Process of 1-[2-(2-Acetylphenyl)phenyl]ethanone

There total 7 articles about 1-[2-(2-Acetylphenyl)phenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-iodoacetophenone (2142-70-3) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 2,2'-diacetylbiphenyl (24017-95-6) + C12H12O3 (854875-53-9)

Guidance literature:

With triethylamine; In water; acetonitrile; at 120 ℃; for 3h; Green chemistry;

DOI:10.1016/j.molcata.2015.02.012

Reference yield: 81.0%

para-bromotoluene (106-38-7) + potassium 2-acetylbenzoate (16727-00-7) → (4,4'-dimethyl-1,1'-biphenyl) (613-33-2) + 4'-methyl-2-acetyl-1,1'-biphenyl (16927-79-0) + 2,2'-diacetylbiphenyl (24017-95-6)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; quinoline; palladium(II) acetylacetonate; 1,10-Phenanthroline; bis-diphenylphosphinomethane; copper(I) bromide; at 160 - 180 ℃; for 24h; Inert atmosphere;

DOI:10.15227/orgsyn.085.0196

Reference yield: 54.0%

1-(2-chlorophenyl)ethanone (2142-68-9) → 2,2'-diacetylbiphenyl (24017-95-6) + trans-9,10-Dihydroxy-9,10-dimethyl-9,10-dihydro-phenanthren (7251-51-6,58131-85-4,58308-05-7,89986-89-0,115586-62-4,115586-63-5)

Guidance literature:

With zinc; bis(triphenylphosphine)nickel(II) chloride; In N,N-dimethyl-formamide; at 60 ℃; for 24h;

DOI:10.1055/s-2007-984543

upstream raw materials:

trans-9,10-Dihydroxy-9,10-dimethyl-9,10-dihydro-phenanthren

1-(2-chlorophenyl)ethanone

2-Chloroanisole

2-iodoacetophenone

Downstream raw materials:

trans-9,10-Dihydroxy-9,10-dimethyl-9,10-dihydro-phenanthren

7-methyl-5H-dibenzocyclohepten-5-one

2-(7-methyl-5H-dibenzocyclohepten-5-yl)-1,3-dioxolane

1-<2'-<(2-methyl-1,3-dioxolan)-2-yl><1,1'-biphenyl>-2-yl>ethanone