Technology Process of 6-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-amine
There total 5 articles about 6-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diphenyl phosphoryl azide; triethylamine;
In
tert-butyl alcohol;
at 25 ℃;
for 18h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 4 h / 25 °C
1.2: pH 0
2.1: triethylamine; diphenyl phosphoryl azide / tert-butyl alcohol / 18 h / 25 °C / Reflux
With
lithium hydroxide monohydrate; diphenyl phosphoryl azide; water; triethylamine;
In
tetrahydrofuran; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogenchloride / methanol / 18 h / Reflux
2.1: dichloromethane / 3 h / 25 °C / Cooling with ice
3.1: potassium hydroxide; copper(II) acetate monohydrate / ethanol / 18 h / 90 °C / Inert atmosphere
4.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 4 h / 25 °C
4.2: pH 0
5.1: triethylamine; diphenyl phosphoryl azide / tert-butyl alcohol / 18 h / 25 °C / Reflux
With
hydrogenchloride; lithium hydroxide monohydrate; diphenyl phosphoryl azide; water; copper(II) acetate monohydrate; triethylamine; potassium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; tert-butyl alcohol;
