(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

Base Information

Chemical Name:(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate
CAS No.:1012060-24-0
Molecular Formula:C₅₁H₆₀ClN₇O₈S₂
Molecular Weight:998.664
Hs Code.:

(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

Synonyms:(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

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Chemical Property of (R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

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Technology Process of (R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

There total 1 articles about (R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.7%

: 406233-35-0
4-(((1R)-3-(dimethylamino)-1-((phenylthio)methyl)propyl)amino)-3-nitrobenzenesulfonamide

: 1012060-23-9
4-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-3-(8-methoxy-8-oxooctanamido)benzoic acid

: 1012060-24-0
(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 25 ℃;

Reference yield: 5.7%

: 1012060-24-0
(R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate

: 1012056-46-0
(R)-N₁-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenyl)-N₈-hydroxyoctanediamide

Guidance literature:: (R)-methyl 8-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-8-oxooctanoate; With hydroxylamine; In methanol; for 0.0833333h; Sonographic reaction;

With acetic acid; In methanol;