Technology Process of 12-amino-N-(benzyloxy)dodecanamide
There total 4 articles about 12-amino-N-(benzyloxy)dodecanamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
tert-butyl (12-(benzyloxyamino)-12-oxododecyl)carbamate;
With
trifluoroacetic acid;
In
chloroform;
at 20 ℃;
for 1h;
Inert atmosphere;
With
ammonia;
pH=9;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide / 1,4-dioxane; water / 24 h / 0 °C / Reflux; Inert atmosphere
1.2: pH 5
2.1: methanol / 0.17 h / 20 °C
3.1: pyridine; 2-thienyl chloride / dichloromethane / 0.08 h / 20 °C / Inert atmosphere
3.2: 1 h / 20 °C / Inert atmosphere
4.1: trifluoroacetic acid / chloroform / 1 h / 20 °C / Inert atmosphere
4.2: pH 9
With
pyridine; 2-thienyl chloride; trifluoroacetic acid; sodium hydroxide;
In
1,4-dioxane; methanol; dichloromethane; chloroform; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridine; 2-thienyl chloride / dichloromethane / 0.08 h / 20 °C / Inert atmosphere
1.2: 1 h / 20 °C / Inert atmosphere
2.1: trifluoroacetic acid / chloroform / 1 h / 20 °C / Inert atmosphere
2.2: pH 9
With
pyridine; 2-thienyl chloride; trifluoroacetic acid;
In
dichloromethane; chloroform;
