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CC-122

Base Information
CC-122

Synonyms:rac-3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione

Suppliers and Price of CC-122
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione
  • 100mg
  • $ 300.00
  • DC Chemicals
  • CC-122(Avadomide) >98%
  • 1 g
  • $ 1700.00
  • DC Chemicals
  • CC-122(Avadomide) >98%
  • 100 mg
  • $ 500.00
  • Crysdot
  • CC-122 95+%
  • 100mg
  • $ 612.00
  • Crysdot
  • CC-122 95+%
  • 50mg
  • $ 369.00
  • Crysdot
  • CC-122 95+%
  • 25mg
  • $ 230.00
  • ChemScene
  • Avadomide 99.53%
  • 100mg
  • $ 750.00
  • ChemScene
  • Avadomide 99.53%
  • 10mg
  • $ 150.00
  • ChemScene
  • Avadomide 99.53%
  • 5mg
  • $ 90.00
  • ChemScene
  • Avadomide 99.53%
  • 50mg
  • $ 450.00
Total 23 raw suppliers
Chemical Property of CC-122
Chemical Property:
  • Melting Point:> 270°C (dec.) 
  • PKA:10.66±0.40(Predicted) 
  • Density:1.58±0.1 g/cm3(Predicted) 
  • Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere 
  • Solubility.:DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) 
Purity/Quality:

99%, *data from raw suppliers

3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione has been shown to treat Diffuse large B-cell lymphoma with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon, a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4.
Technology Process of CC-122

There total 9 articles about CC-122 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 10 wt% Pd(OH)2 on carbon; hydrogen; In N,N-dimethyl-formamide; under 760.051 Torr;
Guidance literature:
With triethylsilane; potassium fluoride; palladium diacetate; In tetrahydrofuran; water; at 20 ℃; for 1h;
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