C₁₃H₈ClN₃

Base Information

• Chemical Name: C₁₃H₈ClN₃
• CAS No.: 1262866-86-3
• Molecular Formula: C₁₃H₈ClN₃
• Molecular Weight: 241.68
• Mol file: 1262866-86-3.mol

Synonyms:C₁₃H₈ClN₃

Chemical Property of C₁₃H₈ClN₃

Chemical Property:

Purity/Quality:

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Technology Process of C₁₃H₈ClN₃

There total 1 articles about C₁₃H₈ClN₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,4-dichloropyrido[3,4-d]pyrimidine (908240-50-6) + phenylboronic acid (98-80-6) → C13H8ClN3 (1262866-86-3)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 120 ℃; for 3h;

Reference yield: 73.0%

C13H8ClN3 (1262866-86-3) → 2-chloro-4-phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

Guidance literature:

With hydrogenchloride; zinc; In water; at 23 ℃; for 20h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.7b03214

Reference yield: 40.0%

4-(carbazol-9-yl)phenylboronic acid (419536-33-7) + C13H8ClN3 (1262866-86-3) → C31H20N4 (1262866-87-4)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 120 ℃; for 24h;

upstream raw materials:

2,4-dichloropyrido[3,4-d]pyrimidine

phenylboronic acid

Downstream raw materials:

C₃₁H₂₀N₄