(S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate

Base Information

Chemical Name:(S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate
CAS No.:1283147-23-8
Molecular Formula:C₁₈H₁₉Cl₂N₃O₃
Molecular Weight:396.273
Hs Code.:

Synonyms:(S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate

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Chemical Property of (S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate

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Technology Process of (S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate

There total 1 articles about (S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.1%

: 1283147-25-0
2-bromo-5-(2,4-dichlorobenzyloxy)pyrimidine

: 1283147-24-9
2-chloro-5-(2,4-dichlorobenzyloxy)pyrimidine

: 53912-83-7
[(2S)-pyrrolidin-2-yl]acetic acid methyl ester

: 1283147-23-8
(S)-methyl 2-(1-(5-(2,4-dichlorobenzyloxy)pyrimidin-2-yl)pyrrolidin-2-yl)acetate

Guidance literature:: 2-bromo-5-(2,4-dichlorobenzyloxy)pyrimidine; 2-chloro-5-(2,4-dichlorobenzyloxy)pyrimidine; [(2S)-pyrrolidin-2-yl]acetic acid methyl ester; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 180 ℃; for 0.5h; Microwave irradiation;

With methanol; In dichloromethane; at 0 ℃;

With sodium hydroxide; In water; pH=5;