benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride

Base Information

• Chemical Name: benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride
• CAS No.: 1413936-84-1
• Molecular Formula: C₁₅H₂₁NO₂*ClH
• Molecular Weight: 283.798
• Mol file: 1413936-84-1.mol

Synonyms:benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride

Chemical Property of benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride

There total 1 articles about benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl 1-((tert-butoxycarbonylamino)methyl)cyclohexanecarboxylate (1413936-83-0) → benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride (1413936-84-1)

Guidance literature:

benzyl 1-((tert-butoxycarbonylamino)methyl)cyclohexanecarboxylate; With trifluoroacetic acid; In dichloromethane; for 2h;

With hydrogenchloride; In diethyl ether;

DOI:10.3762/bjoc.8.142

Reference yield: 75.0%

benzyl 1-(aminomethyl)cyclohexanecarboxylate hydrochloride (1413936-84-1) + N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine (187618-60-6) → benzyl 1-(((4R)-2-aza-7-((2,3-dihydro-2,2,4,6,7-pentamethyl-2H-1-benzofuran-5-yl)sulfonylguanidino))-4-(9H-9-fluorenylmethoxycarboxamido)-3-oxoheptan)cyclohexanecarboxylate (1413936-85-2)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 20 ℃; for 16h;

DOI:10.3762/bjoc.8.142

upstream raw materials:

benzyl 1-((tert-butoxycarbonylamino)methyl)cyclohexanecarboxylate

Downstream raw materials:

benzyl 1-(((4R)-2-aza-7-((2,3-dihydro-2,2,4,6,7-pentamethyl-2H-1-benzofuran-5-yl)sulfonylguanidino))-4-(9H-9-fluorenylmethoxycarboxamido)-3-oxoheptan)cyclohexanecarboxylate