4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine

Base Information

• Chemical Name: 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine
• CAS No.: 174648-74-9
• Molecular Formula: C₂₁H₂₄N₆O
• Molecular Weight: 376.461

Synonyms:4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine

Chemical Property of 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine

Chemical Property:

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Technology Process of 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine

There total 5 articles about 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-furoic acid hydrazide (3326-71-4) → 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine (174648-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 2-methoxy-ethanol / Heating

2: diphenyl ether / 1.5 h / 260 °C

3: 10percent aq. HCl / 3 h / Heating

With hydrogenchloride; In diphenylether; 2-methoxy-ethanol;

DOI:10.1021/jm950746l

Reference yield:

5-Amino-1-[2-(4-isobutyl-phenyl)-ethyl]-1H-pyrazole-4-carbonitrile (1026379-25-8) → 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine (174648-74-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 8 h / Heating

2: 2-methoxy-ethanol / Heating

3: diphenyl ether / 1.5 h / 260 °C

4: 10percent aq. HCl / 3 h / Heating

With hydrogenchloride; In diphenylether; 2-methoxy-ethanol;

DOI:10.1021/jm950746l

Reference yield:

N-{4-Cyano-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-yl}-formimidic acid ethyl ester (1027538-79-9) → 4-(5-Furan-2-yl-2H-[1,2,4]triazol-3-yl)-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-ylamine (174648-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 2-methoxy-ethanol / Heating

2: diphenyl ether / 1.5 h / 260 °C

3: 10percent aq. HCl / 3 h / Heating

With hydrogenchloride; In diphenylether; 2-methoxy-ethanol;

DOI:10.1021/jm950746l

upstream raw materials:

2-furoic acid hydrazide

5-Amino-1-[2-(4-isobutyl-phenyl)-ethyl]-1H-pyrazole-4-carbonitrile

N-{4-Cyano-2-[2-(4-isobutyl-phenyl)-ethyl]-2H-pyrazol-3-yl}-formimidic acid ethyl ester

Furan-2-carboxylic acid {4-imino-1-[2-(4-isobutyl-phenyl)-ethyl]-1,4-dihydro-pyrazolo[3,4-d]pyrimidin-5-yl}-amide

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