(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Base Information

Chemical Name:(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester
CAS No.:910575-75-6
Molecular Formula:C₁₃H₁₅ClO₅
Molecular Weight:286.712
Hs Code.:

Synonyms:(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Suppliers and Price of (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

There total 2 articles about (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 910575-74-5
2-[1-(3-chloro-4-hydroxy-5-methyl-phenyl)-meth-(Z)-ylidene]-succinic acid 1-methyl ester

: 910575-75-6
(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Guidance literature:: With hydrogen; triethylamine; (Z,Z)-cycloocta-1,5-diene(R,R-1,2-bis(2,5-diethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; In methanol; for 8h; under 2585.51 Torr;

Reference yield:

: 107356-10-5
3-Chloro-4-hydroxy-5-methylbenzaldehyde

: 910575-75-6
(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 120 h / 40 °C

2: hydrogen; triethylamine / (Z,Z)-cycloocta-1,5-diene(R,R-1,2-bis(2,5-diethylphospholanyl)benzene)rhodium(I) tetrafluoroborate / methanol / 8 h / 2585.51 Torr

With hydrogen; triethylamine; (Z,Z)-cycloocta-1,5-diene(R,R-1,2-bis(2,5-diethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; In methanol;

Reference yield: 96.0%

: 291509-61-0
3-(4-piperidinyl)-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one

: 910575-75-6
(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester

: 910575-76-7
(S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-4-oxo-4-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-butanoic acid methyl ester

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;