12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol

Base Information

• Chemical Name: 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol
• CAS No.: 137743-86-3
• Molecular Formula: C₂₈H₄₀O₁₀
• Molecular Weight: 536.62

Synonyms:12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol

Chemical Property of 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol

There total 3 articles about 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

12-Benzyloxymethyl-28-methoxy-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1(27),24(28),25-triene (137743-85-2) → 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1(27),24(28),25-trien-28-ol (137743-86-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 20h; Heating;

DOI:10.1021/jo00028a058

Reference yield:

C29H36O11S2 (118356-86-8) → 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1(27),24(28),25-trien-28-ol (137743-86-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) t-BuOK / 1.) THF, rt, 1 h, 2.) THF, 65 deg C, 3 d

2: 67 percent / LiAlH₄ / tetrahydrofuran / 20 h / Heating

With lithium aluminium tetrahydride; potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jo00028a058

Reference yield:

4-Benzyloxymethyl-3,6-dioxa-1,8-octanediol (80525-60-6,118917-64-9) → 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1(27),24(28),25-trien-28-ol (137743-86-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) t-BuOK / 1.) THF, rt, 1 h, 2.) THF, 65 deg C, 3 d

2: 67 percent / LiAlH₄ / tetrahydrofuran / 20 h / Heating

With lithium aluminium tetrahydride; potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jo00028a058

upstream raw materials:

12-Benzyloxymethyl-28-methoxy-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-triene

C₂₉H₃₆O₁₁S₂

4-Benzyloxymethyl-3,6-dioxa-1,8-octanediol

Downstream raw materials:

{12-[4-Decyl-2-(diethoxy-phosphoryl)-phenoxymethyl]-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-yloxy}-acetic acid tert-butyl ester

{12-[4-Decyl-2-(ethoxy-hydroxy-phosphoryl)-phenoxymethyl]-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-yloxy}-acetic acid

[12-(Toluene-4-sulfonyloxymethyl)-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-yloxy]-acetic acid tert-butyl ester

(12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-yloxy)-acetic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 137743-86-3 12-Benzyloxymethyl-2,5,8,11,14,17,20,23-octaoxa-bicyclo[22.3.1]octacosa-1⁽²⁷⁾,24⁽²⁸⁾,25-trien-28-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send