(3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE

Base Information

Chemical Name:(3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE
CAS No.:28495-11-6
Molecular Formula:C9H7 Br2 N O2
Molecular Weight:320.96538
Hs Code.:2926909090
Mol file:28495-11-6.mol

Synonyms:Acetonitrile,(3,5-dibromo-2-hydroxy-4-methoxyphenyl)- (8CI);(3,5-Dibromo-2-hydroxy-4-methoxyphenyl)acetonitrile

Suppliers and Price of (3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE 95.00%
5MG
$ 505.90

Total 2 raw suppliers

Chemical Property of (3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE

Chemical Property:

Vapor Pressure:7.45E-07mmHg at 25°C
Refractive Index:1.617
Boiling Point:396.5°C at 760 mmHg
PKA:6.80±0.50(Predicted)
Flash Point:193.6°C
PSA：53.25000
Density:1.883g/cm³
LogP:2.99188

Purity/Quality:: (3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE

There total 4 articles about (3,5-DIBROMO-2-HYDROXY-4-METHOXY-PHENYL)-ACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 863891-05-8
3,5-dibromo-4-methoxy-2(methoxymethylenoxy)benzylnitrile

: 28495-11-6
3,5-dibromo-2-hydroxy-4-methoxyphenylacetonitrile

Guidance literature:: With toluene-4-sulfonic acid; In methanol;
DOI:10.1021/jo050846r

Reference yield:

: 863891-04-7
3-(3,5-dibromo-4-methoxy-2-methoxymethylenoxyphenyl)-2(E)-(hydroximino)propanoic acid

: 28495-11-6
3,5-dibromo-2-hydroxy-4-methoxyphenylacetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / histamine; DCC / tetrahydrofuran / 16 h

2: 96 percent / p-TSA / methanol

With histamine; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol;
DOI:10.1021/jo050846r

Reference yield:

: 343256-46-2
methyl 3-{3,5-dibromo-4-methoxy-2-(O-methoxymethylenoxy)phenyl}2(E)-(hydroxyimino)propanoate

: 28495-11-6
3,5-dibromo-2-hydroxy-4-methoxyphenylacetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / LiOH / tetrahydrofuran; H₂O / 16 h

2: 95 percent / histamine; DCC / tetrahydrofuran / 16 h

3: 96 percent / p-TSA / methanol

With lithium hydroxide; histamine; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; water;
DOI:10.1021/jo050846r