Technology Process of methyl 4-cyano-2-methyl-4,4-diphenylbutanoate
There total 1 articles about methyl 4-cyano-2-methyl-4,4-diphenylbutanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 4-cyano-2-methyl-4,4-diphenylbutanoate;
With
potassium carbonate;
In
methanol; water;
for 2h;
Heating;
With
sulfuric acid; acetic acid;
for 2h;
Further stages.;
Heating;
DOI:10.1021/jo0706372
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: K2CO3 / H2O; methanol / 2 h / Heating
1.2: 70 percent / AcOH; H2SO4 / 2 h / Heating
2.1: NaH / dimethylformamide / 0.5 h
2.2: 71.7 percent / dimethylformamide
3.1: LDA / tetrahydrofuran / 0.25 h / -70 °C
3.2: 90 percent / tetrahydrofuran / -70 - 20 °C
4.1: 88.8 percent / NaHCO3; NaIO4 / ethanol / 20 °C
5.1: 54.1 percent / methanol / 6 h / Irradiation
With
sodium periodate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jo0706372
