Benzimidazole, 2-ethyl-4(or 7)-methoxy- (6CI)

Base Information

• Chemical Name: Benzimidazole, 2-ethyl-4(or 7)-methoxy- (6CI)
• CAS No.: 114224-42-9
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176.218
• Mol file: 114224-42-9.mol

Synonyms:Benzimidazole,2-ethyl-4(or 7)-methoxy- (6CI)

Chemical Property of Benzimidazole, 2-ethyl-4(or 7)-methoxy- (6CI)

Chemical Property:

• PSA: 37.91000
• LogP: 2.13390

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzimidazole, 2-ethyl-4(or 7)-methoxy- (6CI)

There total 2 articles about Benzimidazole, 2-ethyl-4(or 7)-methoxy- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxybenzene-1,2-diamine (37466-89-0) + propionic acid (802294-64-0,79-09-4) → 2-ethyl-4-methoxy-1(3)H-benzoimidazole (114224-42-9)

Guidance literature:

With hydrogenchloride;

DOI:10.1039/jr9560000569

Reference yield:

→ 2-ethyl-4-methoxy-1(3)H-benzoimidazole (114224-42-9)

Guidance literature:

2,3-Diamino-anisol; 1) Na-Propionat, 2) 4n-HCl <Δ>;

DOI:10.1021/ja01502a006

Reference yield:

2-ethyl-4-methoxy-1(3)H-benzoimidazole (114224-42-9) → 2-ethyl-1(3)H-benzimidazol-4-ol (110392-78-4)

Guidance literature:

With aluminium trichloride; benzene;

DOI:10.1039/jr9560000569

upstream raw materials:

3-methoxybenzene-1,2-diamine

propionic acid

Downstream raw materials:

2-ethyl-1(3)H-benzimidazol-4-ol