1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

Base Information

Chemical Name:1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone
CAS No.:1428968-28-8
Molecular Formula:C₂₃H₂₀N₂O₃S
Molecular Weight:404.489
Hs Code.:

Synonyms:1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

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Chemical Property of 1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

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Technology Process of 1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

There total 3 articles about 1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

: 42883-45-4
2-chloro-1-(1H-indol-3-yl)-2-phenyl-ethanone

: 80213-28-1
3-methylsulfonylaniline hydrochloride

: 1428968-28-8
1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 200 ℃; for 0.5h; Microwave irradiation;

Reference yield:

: 120-72-9
indole

: 1428968-28-8
1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / toluene / 2 h / 55 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 0.5 h / 200 °C / Microwave irradiation

With pyridine; N-ethyl-N,N-diisopropylamine; In toluene; acetonitrile;

Reference yield:

: 2912-62-1
α-chlorophenylacetyl chloride

: 1428968-28-8
1-(1H-indol-3-yl)-2-((3-(methylsulfonyl)phenyl)amino)-2-phenylethanone

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / toluene / 2 h / 55 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 0.5 h / 200 °C / Microwave irradiation

With pyridine; N-ethyl-N,N-diisopropylamine; In toluene; acetonitrile;