2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Base Information

Chemical Name:2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate
CAS No.:1621064-64-9
Molecular Formula:C₂HF₃O₂*C₂₆H₃₇NO₃
Molecular Weight:525.609
Hs Code.:

Synonyms:2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Suppliers and Price of 2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

There total 6 articles about 2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

: 1621064-61-6
2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methyl-1-naphthaldehyde

: 76-05-1
trifluoroacetic acid

: 56-12-2
4-amino-n-butyric acid

: 1621064-64-9
2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Guidance literature:: 2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methyl-1-naphthaldehyde; 4-amino-n-butyric acid; In ethanol; for 2h; Reflux;

With sodium cyanoborohydride; In ethanol; at 50 ℃;

trifluoroacetic acid;

Reference yield:

: 937-05-3
cis-4-tert-butyl-1-cyclohexanol

: 1621064-64-9
2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 0 - 20 °C

2.1: ethanol / 2 h / Reflux

2.2: HPLC / 50 °C

2.3: HPLC

With di-isopropyl azodicarboxylate; triphenylphosphine; In ethanol; dichloromethane;

Reference yield:

: 57404-87-2
3-methoxy-1-methylnaphthalene

: 1621064-64-9
2-(((2-(((trans)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)amino)acetic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: boron trichloride; tetra-(n-butyl)ammonium iodide / dichloromethane / 1 h / -78 - 0 °C / Inert atmosphere

2.1: triphenylphosphine; di-isopropyl azodicarboxylate / toluene / Reflux

3.1: tin(IV) chloride / 1,2-dichloro-ethane / 1 h / 0 °C

3.2: 2 h / 0 - 20 °C

3.3: 1 h

4.1: ethanol / 2 h / Reflux

4.2: HPLC / 50 °C

4.3: HPLC

With di-isopropyl azodicarboxylate; boron trichloride; tin(IV) chloride; tetra-(n-butyl)ammonium iodide; triphenylphosphine; In ethanol; dichloromethane; 1,2-dichloro-ethane; toluene;