4-Pyridinecarboxamide,2,6-dimethyl-(9CI)

Base Information

• Chemical Name: 4-Pyridinecarboxamide,2,6-dimethyl-(9CI)
• CAS No.: 113708-04-6
• Molecular Formula: C8H10 N2 O
• Molecular Weight: 150.18
• Mol file: 113708-04-6.mol

Synonyms:2,6-Dimethylisonicotinamide

Chemical Property of 4-Pyridinecarboxamide,2,6-dimethyl-(9CI)

Chemical Property:

• Boiling Point: 232.6±40.0 °C(Predicted)
• PKA: 15.19±0.50(Predicted)
• PSA: 55.98000
• Density: 1.121±0.06 g/cm3(Predicted)
• LogP: 1.49760

Purity/Quality:

98%min ^*data from raw suppliers

2,6-Dimethylisonicotinamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Pyridinecarboxamide,2,6-dimethyl-(9CI)

There total 1 articles about 4-Pyridinecarboxamide,2,6-dimethyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2,6-dimethylisonicotinonitrile (39965-81-6) → 2,6-dimethylpyridine-4-carboxamide (113708-04-6)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In ethanol; water; at 0 ℃; for 0.5h;

Reference yield:

2,6-dimethylpyridine-4-carboxamide (113708-04-6) → 2,6-dimethylisonicotinonitrile (39965-81-6)

Guidance literature:

2,6-dimethylpyridine-4-carboxamide; With pyridine; trifluoroacetic anhydride; In dichloromethane; at 0 ℃; for 24h;

With sodium hydrogencarbonate; In dichloromethane;

Reference yield:

2,6-dimethylpyridine-4-carboxamide (113708-04-6) → methyl 2,6-dimethylpyridine-4-carboxylate (142896-15-9)

Guidance literature:

With hydrogenchloride; In methanol;

upstream raw materials:

2,6-dimethylisonicotinonitrile

Downstream raw materials:

methyl 2,6-dimethylpyridine-4-carboxylate

2,6-dimethylisonicotinonitrile

Refernces