Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Base Information

Chemical Name:Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester
CAS No.:852066-09-2
Molecular Formula:C₃₃H₆₄NO₁₃P
Molecular Weight:713.844
Hs Code.:

Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Synonyms:Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Suppliers and Price of Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

There total 7 articles about Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 852066-08-1
Octadecanoic acid (R)-1-(6-benzyloxycarbonylamino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentakis-benzyloxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

: 852066-09-2
Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; dichloromethane; for 12h;
DOI:10.1039/b500300h

Reference yield:

: 114218-29-0,129940-53-0,132437-55-9
(+/-)-1-O-allyl-2,3,4,5,6-pentakis-O-benzyl myo-inositol

: 852066-09-2
Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: 74 percent / p-TsOH / Pd/C / ethanol / 2 h / Heating

2.1: 36 percent / pyridine / 16 h / 20 °C

3.1: 99 percent / NaOH / methanol / 0.5 h / 60 - 65 °C

4.1: pivaloyl chloride; pyridine / 0.5 h / 20 °C

4.2: 57 percent / I₂; aq. pyridine / 0.42 h / 20 °C

5.1: 85 percent / H₂ / Pd(OH)2 / aq. methanol; CH₂Cl₂ / 12 h

With pyridine; sodium hydroxide; hydrogen; pivaloyl chloride; toluene-4-sulfonic acid; palladium dihydroxide; palladium on activated charcoal; In methanol; ethanol; dichloromethane;
DOI:10.1039/b500300h

Reference yield:

: 10583-42-3,64681-25-0,64681-27-2,64681-28-3,111466-10-5,111466-15-0,132437-50-4,132437-54-8,135267-01-5,135355-09-8,138923-08-7,138923-09-8,144068-89-3
(+/-)-1-O-allyl-3,4,5,6-tetrakis-O-benzyl myo-inositol

: 852066-09-2
Octadecanoic acid (R)-1-(6-amino-hexanoyloxymethyl)-2-[hydroxy-((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxy-cyclohexyloxy)-phosphoryloxy]-ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: 13 g / NaH / dimethylformamide / 20 °C

2.1: 74 percent / p-TsOH / Pd/C / ethanol / 2 h / Heating

3.1: 36 percent / pyridine / 16 h / 20 °C

4.1: 99 percent / NaOH / methanol / 0.5 h / 60 - 65 °C

5.1: pivaloyl chloride; pyridine / 0.5 h / 20 °C

5.2: 57 percent / I₂; aq. pyridine / 0.42 h / 20 °C

6.1: 85 percent / H₂ / Pd(OH)2 / aq. methanol; CH₂Cl₂ / 12 h

With pyridine; sodium hydroxide; hydrogen; pivaloyl chloride; sodium hydride; toluene-4-sulfonic acid; palladium dihydroxide; palladium on activated charcoal; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b500300h