Technology Process of C20H23NO3
There total 1 articles about C20H23NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C17H19NO3;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran;
at -78 ℃;
Inert atmosphere;
allyl bromide;
In
tetrahydrofuran;
at -40 ℃;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201202643
- Guidance literature:
-
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
In
toluene;
at 40 ℃;
for 2h;
Inert atmosphere;
DOI:10.1002/anie.201202643
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / toluene / 2 h / 40 °C / Inert atmosphere
2.1: lithium borohydride / tetrahydrofuran; methanol / 2 h / 0 °C / Inert atmosphere
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -78 °C / Inert atmosphere
3.2: 1.5 h / -78 - 0 °C / Inert atmosphere
4.1: C23H32N2O2Si; lithium perchlorate / diethyl ether; dichloromethane / 19 h / -40 °C / Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; lithium borohydride; oxalyl dichloride; C23H32N2O2Si; lithium perchlorate; dimethyl sulfoxide;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;
3.1: Swern oxidation / 3.2: Swern oxidation;
DOI:10.1002/anie.201202643
