3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester

Base Information

Chemical Name:3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester
CAS No.:444605-63-4
Molecular Formula:C₂₀H₃₁N₃O₃
Molecular Weight:361.484
Hs Code.:

Synonyms:3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester

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Chemical Property of 3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester

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Technology Process of 3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester

There total 1 articles about 3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 110-85-0
piperazine

: 444605-65-6
tert-butyl 3-(2-bromophenoxy)piperidine-1-carboxylate

: 444605-63-4
3-(2-piperazin-1-yl-phenoxy)-piperidine-1-carboxylic acid tert-buyl ester

Guidance literature:: With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 100 ℃; for 16h;