Technology Process of C15H14O3
There total 5 articles about C15H14O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium hydroxide monohydrate; water;
In
tetrahydrofuran;
at 0 ℃;
for 0.5h;
DOI:10.1021/ol203375y
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride; water / acetonitrile / 0.17 h / Cooling with ice
2: (5aS,10bR)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; sodium acetate; acetic acid / diethyl ether / 22 °C / Inert atmosphere; Darkness
3: lithium hydroxide monohydrate; water / tetrahydrofuran / 0.5 h / 0 °C
With
hydrogenchloride; (5aS,10bR)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; lithium hydroxide monohydrate; water; sodium acetate; acetic acid;
In
tetrahydrofuran; diethyl ether; acetonitrile;
2: Stetter cyclization;
DOI:10.1021/ol203375y
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (5aS,10bR)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; sodium acetate; acetic acid / diethyl ether / 22 °C / Inert atmosphere; Darkness
2: lithium hydroxide monohydrate; water / tetrahydrofuran / 0.5 h / 0 °C
With
(5aS,10bR)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; lithium hydroxide monohydrate; water; sodium acetate; acetic acid;
In
tetrahydrofuran; diethyl ether;
1: Stetter cyclization;
DOI:10.1021/ol203375y
