methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)

Base Information

• Chemical Name: methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)
• CAS No.: 1456719-03-1
• Molecular Formula: C₇₂H₈₂O₂₀S
• Molecular Weight: 1299.5
• Mol file: 1456719-03-1.mol

Synonyms:methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)

Chemical Property of methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)

There total 2 articles about methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

C36H42O7S2 (1456718-96-9) + C38H46O13 → methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside) (1456719-03-1)

Guidance literature:

C₃₆H₄₂O₇S₂; C₃₈H₄₆O₁₃; In dichloromethane; for 0.5h; Molecular sieve;

With N-iodo-succinimide; silver trifluoromethanesulfonate; In tetrahydrofuran; dichloromethane; toluene; at -50 ℃; for 2h; Reagent/catalyst; Temperature; stereoselective reaction;

DOI:10.1002/ejoc.201300681

Reference yield: 73.0%

C36H42O7S2 (1456718-96-9) + methyl [methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate](1→4)-2,3,4-tri-O-benzyl-α-D-glucopyranoside → methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside) (1456719-03-1)

Guidance literature:

C₃₆H₄₂O₇S₂; methyl [methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate](1→4)-2,3,4-tri-O-benzyl-α-D-glucopyranoside; In dichloromethane; at -60 ℃; for 0.5h; Molecular sieve; Inert atmosphere;

With N-iodo-succinimide; silver trifluoromethanesulfonate; In tetrahydrofuran; dichloromethane; at -60 - -50 ℃; for 1h; Reagent/catalyst; Molecular sieve; Inert atmosphere;

DOI:10.3390/molecules21111497

Reference yield: 85.0%

methyl [2,3-di-O-benzyl-4-O-(2-naphthyl)methyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside) (1456719-03-1) → methyl [2,3-di-O-benzyl-6-deoxy-6-C-(ethylsulfonatomethyl)-α-D-glucopyranosyl]-(1→4)-[methyl (2-O-acetyl-3-O-methyl-α-L-idopyranosyl)uronate]-(1→4)-(2,3,6-tri-O-benzyl-α-D-glucopyranoside)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; at 20 ℃; for 0.5h;

DOI:10.3390/molecules21111497

upstream raw materials:

C₃₆H₄₂O₇S₂