ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

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Chemical Name:ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate
CAS No.:881314-56-3
Molecular Formula:C₃₀H₂₈FN₃O₃
Molecular Weight:497.569
Hs Code.:

Synonyms:ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

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Chemical Property of ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

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Technology Process of ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

There total 1 articles about ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 881314-55-2
4-(chloromethyl)-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinoline-3-carbonitrile

: 52605-49-9
sarcosine ethyl ester hydrochloride

: 881314-56-3
ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

Guidance literature:: With potassium carbonate; In tetrahydrofuran; for 16h; Heating / reflux;

Reference yield: 7.0%

: 881314-56-3
ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate

: 881314-57-4
N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycine

Guidance literature:: ethyl N-{[3-cyano-2-(2'-ethoxybiphenyl-4-yl)-6-fluoroquinolin-4-yl]methyl}-N-methylglycinate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 16h;

With hydrogenchloride; In water; pH=3;