N-formyl-D-alloisoleucine 2-chloroethyl ester

Base Information

• Chemical Name: N-formyl-D-alloisoleucine 2-chloroethyl ester
• CAS No.: 630104-04-0
• Molecular Formula: C₉H₁₆ClNO₃
• Molecular Weight: 221.684
• Mol file: 630104-04-0.mol

Synonyms:N-formyl-D-alloisoleucine 2-chloroethyl ester

Chemical Property of N-formyl-D-alloisoleucine 2-chloroethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N-formyl-D-alloisoleucine 2-chloroethyl ester

There total 1 articles about N-formyl-D-alloisoleucine 2-chloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

(S)-2-Formylamino-3-methyl-pentanoic acid 2-chloro-ethyl ester → N-formyl-L-isoleucine (4101-35-3,89810-44-6) + N-formyl-D-alloisoleucine 2-chloroethyl ester (630104-04-0)

Guidance literature:

With sodium hydroxide; Alcalase; In water; at 39 ℃; for 2.5h; pH=7.8; Enzymatic reaction;

DOI:10.1016/j.tetasy.2003.08.009

Reference yield:

N-formyl-D-alloisoleucine 2-chloroethyl ester (630104-04-0) → D-alloisoleucine (1509-35-9,959215-79-3,18875-42-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / hydrochloric acid / 5 h / 90 °C

2: NaOH / dioxane; H₂O / 1.5 h / Heating

With hydrogenchloride; sodium hydroxide; In 1,4-dioxane; water;

DOI:10.1016/j.tetasy.2003.08.009

Downstream raw materials:

D-alloisoleucine