1-Chloro-5-iodo-2,4-dimethoxybenzene

Base Information

• Chemical Name: 1-Chloro-5-iodo-2,4-dimethoxybenzene
• CAS No.: 96694-60-9
• Molecular Formula: C₈H₈ClIO₂
• Molecular Weight: 298.508
• European Community (EC) Number: 635-767-6
• NSC Number: 88143

Synonyms:1-chloro-5-iodo-2,4-dimethoxybenzene;96694-60-9;NSC88143;NSC-88143;AKOS024332359;CS-0249127;E89389;EN300-4256017;Z1269206248

Chemical Property of 1-Chloro-5-iodo-2,4-dimethoxybenzene

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 297.92575
• Heavy Atom Count: 12
• Complexity: 145

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1Cl)I)OC

Technology Process of 1-Chloro-5-iodo-2,4-dimethoxybenzene

There total 1 articles about 1-Chloro-5-iodo-2,4-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-Dimethoxybenzene (151-10-0) → 1-chloro-5-iodo-2,4-dimethoxybenzene (96694-60-9)

Guidance literature:

1,3-Dimethoxybenzene; With N-chloro-succinimide; at 20 ℃; for 5h;

With N-iodo-succinimide; at 20 ℃; for 0.5h; regioselective reaction;

DOI:10.1021/acs.joc.7b02920

Reference yield: 87.0%

1-chloro-5-iodo-2,4-dimethoxybenzene (96694-60-9) + 3-Butyn-1-ol (927-74-2) → 4-(5-chloro-2,4-dimethoxyphenyl)but-3-yn-2-ol

Guidance literature:

With triphenylphosphine; copper(l) chloride; palladium dichloride; In diethylamine; at 20 ℃; for 0.5h; Inert atmosphere; Cooling with ice;

DOI:10.1002/anie.201301529

Reference yield: 69.0%

C27H27BO3 + 1-chloro-5-iodo-2,4-dimethoxybenzene (96694-60-9) → C29H23ClO3

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; at 110 ℃; for 24h; Inert atmosphere;

upstream raw materials:

1,3-Dimethoxybenzene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 96694-60-9 1-chloro-5-iodo-2,4-dimethoxybenzene

Send

Send

Metric Ton KG G Pound L ML

Send

Send