3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Base Information

Chemical Name:3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester
CAS No.:1046831-99-5
Molecular Formula:C₁₃H₂₃BO₂
Molecular Weight:222.135
Hs Code.:

Synonyms:3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Suppliers and Price of 3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,4,5,5-Tetramethyl-2-(5-methyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane
250mg
$ 165.00

Chemenu
4,4,5,5-Tetramethyl-2-(5-methylcyclohex-1-en-1-yl)-1,3,2-dioxaborolane 95+%
1g
$ 2059.00

Total 3 raw suppliers

Chemical Property of 3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

4,4,5,5-Tetramethyl-2-(5-methyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4,4,5,5-Tetramethyl-2-(5-methyl-1-cyclohexen-1-yl)-1,3,2-dioxaborolane is a reagent that is used in the preparation of azaindole derivatives as c-Jun N-terminal kinase inhibitors. These inhibitors are useful in the treatment of neurodegenerative disorders, inflammatory diseases and autoimmune diseases.

Technology Process of 3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

There total 3 articles about 3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61676-62-8
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 63883-80-7
3-Methylcyclohexanon-tosylhydrazon

: 1046831-99-5
3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Guidance literature:: 3-Methylcyclohexanon-tosylhydrazon; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at -78 - 25 ℃; for 3h;

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In hexane; at -78 ℃;
DOI:10.1039/d0gc01514h

Reference yield:

: 1046832-00-1
3-methylcyclohexene-1-boronic acid pinacol ester

: 1046831-99-5
3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Guidance literature:

Reference yield:

: 591-24-2,625-96-7
3-Methylcyclohexanone

: 1046831-99-5
3-methyl-1-cyclohexen-1-ylboronic acid pinacol ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 2 h / 70 °C / Reflux

2.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / hexane / 3 h / -78 - 25 °C

2.2: -78 °C

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In methanol; hexane;
DOI:10.1039/d0gc01514h