Technology Process of CCIC15
There total 3 articles about CCIC15 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 168h;
Inert atmosphere;
DOI:10.1002/jlcr.3095
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C
1.2: 2 h / 20 °C
2.1: sodium L-ascorbate; copper(ll) sulfate pentahydrate / N,N-dimethyl-formamide / 168 h / 20 °C / Inert atmosphere
With
copper(ll) sulfate pentahydrate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; sodium L-ascorbate;
In
N,N-dimethyl-formamide;
2.1: |Huisgen Cycloaddition;
DOI:10.1002/jlcr.3095
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C
1.2: 2 h / 20 °C
2.1: sodium L-ascorbate; copper(ll) sulfate pentahydrate / N,N-dimethyl-formamide / 168 h / 20 °C / Inert atmosphere
With
copper(ll) sulfate pentahydrate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; sodium L-ascorbate;
In
N,N-dimethyl-formamide;
2.1: |Huisgen Cycloaddition;
DOI:10.1002/jlcr.3095
