4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

Base Information

Chemical Name:4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester
CAS No.:1443417-14-8
Molecular Formula:C₂₆H₃₃NO₆
Molecular Weight:455.551
Hs Code.:

Synonyms:4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

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Chemical Property of 4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

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Technology Process of 4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

There total 3 articles about 4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1443417-18-2
C₃₄H₃₉NO₈

: 1443417-14-8
4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; for 4h;

Reference yield:

: 18496-54-3
phenylbutyric acid chloride

: 1443417-14-8
4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 4 h / 0 °C

2: benzotriazol-1-ol; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h

3: 5%-palladium/activated carbon; hydrogen / tetrahydrofuran / 4 h

With dmap; 5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 864811-35-8
4-phenyl-butyric acid 2-hydroxy-3-(4-phenyl-butyryloxy)-propyl ester

: 1443417-14-8
4-phenyl-butyric acid 2-((R)-2-amino-propionyloxy)-3-(4-phenyl-butyryloxy)-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h

2: 5%-palladium/activated carbon; hydrogen / tetrahydrofuran / 4 h

With dmap; 5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane;