methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

Base Information

Chemical Name:methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate
CAS No.:1359869-62-7
Molecular Formula:C₁₇H₁₄N₂O₄
Molecular Weight:310.309
Hs Code.:

Synonyms:methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

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Chemical Property of methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

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Technology Process of methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

There total 5 articles about methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1359869-61-6
C₁₇H₁₄N₂O₅

: 1359869-62-7
methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In methanol; at 20 ℃; for 2h;

Reference yield:

: C₁₇H₁₆N₂O₄

: 1359869-62-7
methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; at 70 ℃; for 2h;
DOI:10.1055/s-0039-1690699

Reference yield:

: 1571-08-0
methyl 4-formylbenzoate

: 1359869-62-7
methyl 4-(4-(methoxycarbonyl)phenyl)pyrrolo[1,2-a]pyrazine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonia / zinc trifluoromethanesulfonate / tetrahydrofuran / 0 °C

1.2: 1 h / 0 - 20 °C

1.3: 2 h / Reflux

2.1: benzene / 4 h / 95 °C

3.1: hydrogen; acetic acid / palladium on activated charcoal / methanol / 2 h / 20 °C

With ammonia; hydrogen; acetic acid; palladium on activated charcoal; zinc trifluoromethanesulfonate; In tetrahydrofuran; methanol; benzene;