4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

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Chemical Name:4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester
CAS No.:922732-12-5
Molecular Formula:C₂₀H₂₃N₃O₇
Molecular Weight:417.419
Hs Code.:

Synonyms:4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

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Technology Process of 4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

There total 2 articles about 4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 922732-11-4
(2S,4R)-2-((1R,2S)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)-4-(4-nitrobenzoyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester

: 922732-12-5
4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane;

Reference yield: 98.0%

: 922732-12-5
4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

Guidance literature:

Reference yield: 91.0%

: 922726-64-5
hept-6-enyl-(p-methoxybenzyl)amine

: 922732-12-5
4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester

: 922732-13-6
4-nitrobenzoic acid (3R,5S)-5-((1R,2S)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)-1-[hept-6-enyl-(4-methoxybenzyl)carbamoyl]pyrrolidin-3-yl ester

Guidance literature:: phosgene; 4-nitrobenzoic acid (3R,5S)-5-((R)-1-ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)pyrrolidin-3-yl ester; With sodium hydrogencarbonate; In tetrahydrofuran; water; toluene; for 1h;

hept-6-enyl-(p-methoxybenzyl)amine; With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃;