(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

Base Information

Chemical Name:(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
CAS No.:195453-93-1
Molecular Formula:C₁₆H₁₉NO₆
Molecular Weight:321.33
Hs Code.:

Synonyms:(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

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Chemical Property of (S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

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Technology Process of (S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

There total 1 articles about (S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 195453-92-0
(S)-2-Allyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

: 195453-93-1
(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

Guidance literature:: With Jones reagent (CrO₃/H₂SO₄); ozone; Yield given. Multistep reaction; 1.) acetone, -20 deg C, 20 min; 2.) aceton, 0 deg C;
DOI:10.1002/hlca.19970800514

Reference yield: 100.0%

: 195453-93-1
(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

: (S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

Guidance literature:: With lithium hydroxide; In methanol; water; for 6h; Ambient temperature;
DOI:10.1002/hlca.19970800514

Reference yield:

: 195453-93-1
(S)-2-Carboxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

: (S)-2-tert-Butoxycarbonylmethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: conc. H₂SO₄

2: LiOH*H₂O / methanol; H₂O

With lithium hydroxide; sulfuric acid; In methanol; water;
DOI:10.1002/hlca.19970800514