N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide
CAS No.:1431881-98-9
Molecular Formula:C₂₄H₂₀FIN₂O₂S
Molecular Weight:546.404
Hs Code.:

Synonyms:N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Suppliers and Price of N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

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Technology Process of N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

There total 4 articles about N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 852292-27-4
N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

: 16886-08-1
1-allylindole

: 1431881-98-9
N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Guidance literature:: With iodine; caesium carbonate; In acetonitrile; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1039/c2cc38342j

Reference yield:

: 16886-08-1
1-allylindole

: 727-31-1
N-(4-fluorophenyl)-4-methylbenzenesulfonamide

: 1431881-98-9
N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Guidance literature:: With iodine; caesium carbonate; In acetonitrile; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1039/c4ob00140k

Reference yield:

: 61272-76-2
4-fluoro-2-iodoaniline

: 1431881-98-9
N-(1-allyl-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 3 h / 0 - 20 °C / Inert atmosphere

2: caesium carbonate; iodine / acetonitrile / 20 °C / Inert atmosphere

With pyridine; iodine; caesium carbonate; In acetonitrile;
DOI:10.1039/c4cc08911a