methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Base Information

Chemical Name:methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate
CAS No.:1264836-31-8
Molecular Formula:C₄₁H₄₁N₅O₉S₂
Molecular Weight:811.937
Hs Code.:

methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Synonyms:methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Suppliers and Price of methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

There total 5 articles about methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 37517-81-0
3-chloro-3-oxopropanoic acid methyl ester

: 1264836-30-7
N-(3-((4-(4-amino-3-(2-(pyridin-3-yl)ethoxy)phenoxy)benzyl)(4-cyanobenzyl)amino)-2-methylphenyl)-N-(methylsulfonyl)methanesulfonamide

: 1264836-31-8
methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 1264836-26-1
N-(3-((4-(allyloxy)benzyl)(4-cyanobenzyl)amino)-2-methylphenyl)methanesulfonamide

: 1264836-31-8
methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / dichloromethane / 40 °C

2: phenylsilane / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / dichloromethane / 4 h / 20 °C / Inert atmosphere

3: triethylamine; pyridine / copper diacetate / dichloromethane / 48 h / 20 °C / Molecular sieve

4: ammonium chloride; iron / ethyl acetate; ethanol; water / 1 h / 75 °C

5: triethylamine / dichloromethane / 0 - 20 °C

With pyridine; phenylsilane; iron; ammonium chloride; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper diacetate; In ethanol; dichloromethane; water; ethyl acetate;

Reference yield:

: 1264836-27-2
N-(3-((4-cyanobenzyl)(4-hydroxybenzyl)amino)-2-methylphenyl)-N-(methylsulfonyl)methanesulfonamide

: 1264836-31-8
methyl 3-(4-(4-(((4-cyanobenzyl)(2-methyl-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)amino)methyl)phenoxy)-2-(2-(pyridin-3-yl)ethoxy)phenylamino)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; pyridine / copper diacetate / dichloromethane / 48 h / 20 °C / Molecular sieve

2: ammonium chloride; iron / ethyl acetate; ethanol; water / 1 h / 75 °C

3: triethylamine / dichloromethane / 0 - 20 °C

With pyridine; iron; ammonium chloride; triethylamine; copper diacetate; In ethanol; dichloromethane; water; ethyl acetate;