TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside

Base Information

• Chemical Name: TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside
• CAS No.: 1301718-54-6
• Molecular Formula: C₂₀H₃₃NO₇Si
• Molecular Weight: 427.57
• Mol file: 1301718-54-6.mol

Synonyms:TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside

Chemical Property of TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside

There total 5 articles about TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-butyldimethylsilyl 3,4,6-tri-O-acetyl-2-(benzyloxycarbonyl)amino-2-deoxy-β-D-glucopyranoside (816451-36-2) → TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside (1301718-54-6)

Guidance literature:

With methanol; sodium methylate;

DOI:10.2174/157017811794557877 DOI:10.2174/157017811799304331

Reference yield:

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(benzyloxycarbonyl)amino-α/β-D-glucopyranoside (5348-99-2,35946-66-8,82264-19-5,100483-05-4) → TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside (1301718-54-6)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazinium monoacetate / N,N-dimethyl-formamide

2: 1H-imidazole

3: methanol; sodium methylate

With 1H-imidazole; methanol; sodium methylate; hydrazinium monoacetate; In N,N-dimethyl-formamide;

DOI:10.2174/157017811794557877

Reference yield:

3,4,6-tri-O-acetyl-2-{[(benzyloxy)carbonyl]amino}-2-deoxy-β-D-glucopyranose (99194-76-0,140183-53-5) → TBDMS 2-deoxy-2-(N-benzyloxycarbonylamino)-β-D-glucopyranoside (1301718-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1H-imidazole

2: sodium methylate / methanol

With 1H-imidazole; sodium methylate; In methanol;

DOI:10.2174/157018011796235220

upstream raw materials:

tert-butyldimethylsilyl 3,4,6-tri-O-acetyl-2-(benzyloxycarbonyl)amino-2-deoxy-β-D-glucopyranoside

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(benzyloxycarbonyl)amino-α/β-D-glucopyranoside

2-benzyloxycarbonylamino-2-deoxy-3,4,6-tri-O-acetyl-D-glucopyranose

3,4,6-tri-O-acetyl-2-{[(benzyloxy)carbonyl]amino}-2-deoxy-β-D-glucopyranose