1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide

Base Information

• Chemical Name: 1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide
• CAS No.: 865709-79-1
• Molecular Formula: C₁₃H₁₆N₆OS₂
• Molecular Weight: 336.442
• Mol file: 865709-79-1.mol

Synonyms:1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide

Chemical Property of 1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide

There total 1 articles about 1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl [(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetate (476211-49-1) → 1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide (865709-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / NH₂NH₂*H₂O / ethanol / 24 h / 20 °C

2: 94 percent / methanol / 96 h / 20 °C

With hydrazine hydrate; In methanol; ethanol;

DOI:10.1135/cccc20050051

Reference yield: 88.0%

1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide (865709-79-1) → 5-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4-(p-tolyl)-4H-1,2,4-triazole-3(2H)-thione

Guidance literature:

With sodium hydroxide; for 2h; Heating;

DOI:10.1135/cccc20050051

Reference yield: 83.0%

1-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}-4-(p-tolyl)thiosemicarbazide (865709-79-1) → 5-{[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-2-(p-tolylamino)-1,3,4-thiadiazole

Guidance literature:

With sulfuric acid; at 20 ℃; for 240h;

DOI:10.1135/cccc20050051

upstream raw materials:

ethyl [(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetate