4-Chloro-6-fluoro-3-nitro-quinoline

Base Information

Chemical Name:4-Chloro-6-fluoro-3-nitro-quinoline
CAS No.:99010-07-8
Molecular Formula:C9H4 Cl F N2 O2
Molecular Weight:226.594
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30445405
Wikidata:Q82263791
Mol file:99010-07-8.mol

Synonyms:4-chloro-6-fluoro-3-nitroquinoline;4-chloro-6-fluoro-3-nitro-quinoline;99010-07-8;SCHEMBL2244805;DTXSID30445405;JTKXABQYVUAKJV-UHFFFAOYSA-N;MFCD10687171;AKOS026727643;SB70239;AS-37317;CS-0232757;EN300-128523

Suppliers and Price of 4-Chloro-6-fluoro-3-nitro-quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
4-Chloro-6-fluoro-3-nitroquinoline 97%
1g
$ 817.00

American Custom Chemicals Corporation
4-CHLORO-6-FLUORO-3-NITRO-QUINOLINE 95.00%
1G
$ 959.70

Alichem
4-Chloro-6-fluoro-3-nitroquinoline
10g
$ 1606.66

Alichem
4-Chloro-6-fluoro-3-nitroquinoline
5g
$ 1093.44

Alichem
4-Chloro-6-fluoro-3-nitroquinoline
25g
$ 2626.47

AK Scientific
4-Chloro-6-fluoro-3-nitro-quinoline
2.5g
$ 1609.00

Total 7 raw suppliers

Chemical Property of 4-Chloro-6-fluoro-3-nitro-quinoline

Chemical Property:

PSA：58.71000
LogP:3.45870
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:225.9945332
Heavy Atom Count:15
Complexity:261

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-6-fluoro-3-nitroquinoline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=C(C(=C2C=C1F)Cl)[N+](=O)[O-]

Technology Process of 4-Chloro-6-fluoro-3-nitro-quinoline

There total 3 articles about 4-Chloro-6-fluoro-3-nitro-quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.7%

: 628284-75-3,866472-95-9
6-fluoro-3-nitroquinolin-4-ol

: 99010-07-8
4-chloro-6-fluoro-3-nitroquinoline

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield:

: 6-Fluoro-3-nitro-1H-quinolin-4-one

: 99010-07-8
4-chloro-6-fluoro-3-nitroquinoline

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1021/jm9600609

Reference yield:

: (E)-5-fluoro-2-((2-nitrovinyl)amino)benzoic acid

: 99010-07-8
4-chloro-6-fluoro-3-nitroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetic anhydride / 15 - 90 °C

2: trichlorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C

With potassium carbonate; trichlorophosphate; In acetic anhydride; N,N-dimethyl-formamide;