1-Heptanol, 2,4-dimethyl-

Base Information

• Chemical Name: 1-Heptanol, 2,4-dimethyl-
• CAS No.: 98982-97-9
• Molecular Formula: C9H20 O
• Molecular Weight: 144.257
• Mol file: 98982-97-9.mol

Synonyms:2,4-Dimethyl-1-heptanol

Chemical Property of 1-Heptanol, 2,4-dimethyl-

Chemical Property:

• PSA: 20.23000
• LogP: 2.44110

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Heptanol, 2,4-dimethyl-

There total 4 articles about 1-Heptanol, 2,4-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + trimethylaluminum (75-24-1) → 2,4,6,8-tetramethylundecan-1-ol (877803-48-0) + 2-methylpentan-1-ol (105-30-6) + C18H38O + C21H44O + C24H50O + C27H56O + C30H62O + C33H68O + 2,4-dimethylheptan-1-ol (98982-97-9) + 2,4,6-trimethylnonan-1-ol (83474-29-7)

Guidance literature:

propene; trimethylaluminum; With (η⁵–neomenthylindenyl)₂ZrCl₂; at 20 ℃; for 24h; under 750.075 Torr; Inert atmosphere;

With oxygen; at 0 ℃; for 26h;

With hydrogenchloride; In water; regioselective reaction;

DOI:10.1016/j.catcom.2018.10.032

Reference yield:

methyl (2R,4S,6S)-2,4-dimethyl-6-tosyloxyheptanoate (110444-39-8) → (2R,4R)-2,4-dimethyl-1-heptanol (18450-73-2,18450-74-3,98982-97-9,110507-98-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Yield given; Ambient temperature;

DOI:10.1016/S0040-4020(01)88158-8

Reference yield:

(2R,4S,6S,)-2,4-dimethyl-6-heptanolide (110397-90-5,110547-93-8,133868-61-8) → (2R,4R)-2,4-dimethyl-1-heptanol (18450-73-2,18450-74-3,98982-97-9,110507-98-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 15.09 g / conc. H₂SO₄ / methanol / 1 h / Ambient temperature

2: 26.79 g / pyridine / 4 h / 0 - 5 °C

3: LAH / diethyl ether / Ambient temperature

With lithium aluminium tetrahydride; sulfuric acid; In pyridine; methanol; diethyl ether;

DOI:10.1016/S0040-4020(01)88158-8

upstream raw materials:

methyl (2R,4S,6S)-2,4-dimethyl-6-tosyloxyheptanoate

(2R,4S,6S,)-2,4-dimethyl-6-heptanolide

methyl (2R,4S,6S)-6-hydroxy-2,4-dimethylheptanoate

propene

Downstream raw materials:

(2R,3R)-2,4-dimethylheptyl tosylate

Refernces

• 1、 Mori, Kenji,Kuwahara, Shigefumi. "STEREOCHEMISTRY OF LARDOLURE. THE AGGREGATION PHEROMONE OF THE ACARID MITE, LARDOGLYPHUS KONOI". . p. 5545 - 5550. Retrieved 2007/10/02.