2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

Base Information

Chemical Name:2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline
CAS No.:1234509-91-1
Molecular Formula:C₁₉H₁₅ClN₄O
Molecular Weight:350.807
Hs Code.:

Synonyms:2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

Suppliers and Price of 2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

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Technology Process of 2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

There total 5 articles about 2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1234509-80-8
C₁₁H₉ClN₄O

: 536-74-3
phenylacetylene

: 1234509-91-1
2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1016/j.ejmech.2010.04.002

Reference yield:

: 1447170-27-5
C₁₁H₉ClINO

: 1234509-91-1
2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / acetone; water

2: L-sodium ascorbate; copper(ll) sulfate pentahydrate / water / 20 °C

With sodium azide; copper(ll) sulfate pentahydrate; L-sodium ascorbate; In water; acetone;
DOI:10.2174/1570180811310040008

Reference yield:

: 948291-11-0
2-chloro-3-(chloromethyl)-6-methoxyquinoline

: 1234509-91-1
2-chloro-6-methoxy-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: potassium iodide / acetone / 2 h / Reflux

2: sodium azide / acetone; water

3: L-sodium ascorbate; copper(ll) sulfate pentahydrate / water / 20 °C

With sodium azide; copper(ll) sulfate pentahydrate; L-sodium ascorbate; potassium iodide; In water; acetone;
DOI:10.2174/1570180811310040008