1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

Base Information

Chemical Name:1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde
CAS No.:1356998-31-6
Molecular Formula:C₁₃H₁₁F₃N₂O₂
Molecular Weight:284.238
Hs Code.:

Synonyms:1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

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Chemical Property of 1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

Chemical Property:

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Technology Process of 1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

There total 2 articles about 1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 349-95-1
4-(trifluoromethyl)benzylic alcohol

: 117007-77-9
5-chloro-1-methyl-1H-pyrazole-4-carbaldehyde

: 1356998-31-6
1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

Guidance literature:: 4-(trifluoromethyl)benzylic alcohol; With potassium tert-butylate; In tetrahydrofuran; for 0.166667h; Inert atmosphere; Cooling with ice;

5-chloro-1-methyl-1H-pyrazole-4-carbaldehyde; In tetrahydrofuran; at 20 ℃; for 4h; Cooling with ice;

Reference yield:

: 117007-77-9
5-chloro-1-methyl-1H-pyrazole-4-carbaldehyde

: 1356998-31-6
1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; for 0.333333h; Cooling with ice;

5-chloro-1-methyl-1H-pyrazole-4-carbaldehyde; In tetrahydrofuran; for 3h; Cooling with ice;

Reference yield:

: 1356998-31-6
1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazole-4-carbaldehyde

: 1359029-29-0
1-methyl-5-{[4-(trifluoromethyl)benzyl]oxy}-1H-pyrazol-4-carboxylic acid

Guidance literature:: With sodium chlorite; potassium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 20 ℃; for 3.5h;