4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide

Base Information

• Chemical Name: 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide
• CAS No.: 1422573-60-1
• Molecular Formula: C₂₈H₂₄Br₂N₄O₂
• Molecular Weight: 608.332
• Mol file: 1422573-60-1.mol

Synonyms:4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide

Chemical Property of 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide

There total 8 articles about 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

C12H4Br2Cl2N2O2 + N-ethyl-N-phenylamine (103-69-5) → 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide (1422573-60-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 40 - 50 ℃;

DOI:10.1007/s11172-012-0124-4

Reference yield:

4,4′-dibromo-6,6′-dimethyl-2,2′-bipyridine (144342-45-0) → 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide (1422573-60-1)

Guidance literature:

Multi-step reaction with 3 steps

1: chromium(VI) oxide; sulfuric acid / 2 h / 70 °C

2: thionyl chloride / N,N-dimethyl-formamide / 2.5 h / Reflux

3: triethylamine / tetrahydrofuran / 40 - 50 °C

With chromium(VI) oxide; thionyl chloride; sulfuric acid; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1007/s11172-012-0124-4

Reference yield:

6,6'-dimethyl-2,2'-bipyridine (4411-80-7) → 4,4'-dibromo-N,N'-diethyl-N,N'-diphenyl-2,2'-bipyridyl-6,6-dicarboxamide (1422573-60-1)

Guidance literature:

Multi-step reaction with 7 steps

1: acetic acid; dihydrogen peroxide / water / 7 h / 70 °C

2: sulfuric acid; nitric acid / 2 h / 90 °C

3: Acetyl bromide / tetrachloromethane / 4 h / Reflux

4: phosphorus tribromide / dichloromethane / 20 h / 20 °C

5: chromium(VI) oxide; sulfuric acid / 2 h / 70 °C

6: thionyl chloride / N,N-dimethyl-formamide / 2.5 h / Reflux

7: triethylamine / tetrahydrofuran / 40 - 50 °C

With chromium(VI) oxide; thionyl chloride; Acetyl bromide; sulfuric acid; dihydrogen peroxide; nitric acid; phosphorus tribromide; acetic acid; triethylamine; In tetrahydrofuran; tetrachloromethane; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1007/s11172-012-0124-4

upstream raw materials:

4,4′-dibromo-6,6′-dimethyl-2,2′-bipyridine

4,4'-dibromo-2,2'-dipyridyl-6,6'-dicarboxylic acid

6,6'-dimethyl-2,2'-bipyridine

N-ethyl-N-phenylamine