Technology Process of (3S,11R,14RS)-1-benzyloxy-14,15-epoxy-3,11,15-trimethyl-7-hexadecyne
There total 8 articles about (3S,11R,14RS)-1-benzyloxy-14,15-epoxy-3,11,15-trimethyl-7-hexadecyne which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1271/bbb.120436
- Guidance literature:
-
Multi-step reaction with 7 steps
1: lithium aluminium tetrahydride / diethyl ether
2: pyridine
3: sodium iodide / N,N-dimethyl-formamide
4: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 2 h / Reflux
5: potassium carbonate / methanol; water
6: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
7: 3-chloro-benzenecarboperoxoic acid / dichloromethane
With
pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; n-butyllithium; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; sodium iodide;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1271/bbb.120436
- Guidance literature:
-
Multi-step reaction with 6 steps
1: periodic acid dihydrate / diethyl ether; tetrahydrofuran / 1 h / 0 - 20 °C
2: lithium aluminium tetrahydride / diethyl ether
3: pyridine
4: sodium iodide / N,N-dimethyl-formamide
5: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
6: 3-chloro-benzenecarboperoxoic acid / dichloromethane
With
pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; n-butyllithium; periodic acid dihydrate; 3-chloro-benzenecarboperoxoic acid; sodium iodide;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1271/bbb.120436
