1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester

Base Information

• Chemical Name: 1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester
• CAS No.: 168086-67-7
• Molecular Formula: C₂₄H₂₆Cl₃NO₄Si
• Molecular Weight: 526.919
• Mol file: 168086-67-7.mol

Synonyms:1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester

Chemical Property of 1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester

There total 1 articles about 1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester (168086-66-6) + 2,4,6-trichlorobenzoyl chloride (4136-95-2) + ammonium chloride → 1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester (168086-67-7)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; ethyl acetate; toluene;

Reference yield:

1-(2,4,6-trichlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester (168086-67-7) + ammonium chloride → 5-methoxy-2-methyl-1-(2,4,6-trichlorobenzoyl)-1H-indole-3-acetic acid (168086-64-4)

Guidance literature:

With hydrogenchloride; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane;

upstream raw materials:

5-methoxy-2-methyl-3-indolyl acetic acid 2-(trimethylsilyl)ethyl ester

2,4,6-trichlorobenzoyl chloride

Downstream raw materials:

5-methoxy-2-methyl-1-(2,4,6-trichlorobenzoyl)-1H-indole-3-acetic acid