C₅₃H₈₁NO₁₅

Base Information

• Chemical Name: C₅₃H₈₁NO₁₅
• CAS No.: 484670-76-0
• Molecular Formula: C₅₃H₈₁NO₁₅
• Molecular Weight: 972.224
• Mol file: 484670-76-0.mol

Synonyms:C₅₃H₈₁NO₁₅

Chemical Property of C₅₃H₈₁NO₁₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₈₁NO₁₅

There total 4 articles about C₅₃H₈₁NO₁₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C56H85NO15 (484670-74-8) → C53H81NO15 (484670-76-0)

Guidance literature:

With pyridinium p-toluenesulfonate; In water; acetonitrile; at 68 ℃; for 46h;

Reference yield:

C55H81NO15 + methyllithium (917-54-4) → C53H81NO15 (484670-76-0)

Guidance literature:

methyllithium; With copper(I) bromide dimethylsulfide complex; In diethyl ether; at -78 - -20 ℃;

C₅₅H₈₁NO₁₅; In diethyl ether; at 0 - 5 ℃; for 12h;

With pyridinium p-toluenesulfonate; In water; acetonitrile; at 70 ℃; for 48h;

DOI:10.1016/j.bmc.2006.04.032

Reference yield:

C55H81NO14 → C53H81NO15 (484670-76-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 99 percent / 3-chloroperbenzoic acid / CH₂Cl₂ / 21.5 h / 0 - 20 °C

2.1: 83 percent / NaHSO₃ / tetrahydrofuran; H₂O / 0.5 h

3.1: CuBr*Me₂S / diethyl ether / -78 - -20 °C

3.2: diethyl ether / 12 h / 0 - 5 °C

3.3: 3.52 g / pyridinium para-toluenesulfonate / acetonitrile; H₂O / 48 h / 70 °C

With copper(I) bromide dimethylsulfide complex; sodium hydrogensulfite; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; dichloromethane; water;

DOI:10.1016/j.bmc.2006.04.032

upstream raw materials:

methyllithium

C₅₆H₈₅NO₁₅

Downstream raw materials:

Benzoic acid (2S,3R,4S,6R)-2-((E)-(3R,5R,6R,7R,9R,13S,14R)-13,14-diethyl-13-hydroxy-7-methoxy-3,5,7,9,11-pentamethyl-2,4,10-trioxo-oxacyclotetradec-11-en-6-yloxy)-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester

Benzoic acid (2S,3R,4S,6R)-2-((E)-(3R,4S,5S,6R,7R,9R,13S,14R)-13,14-diethyl-4,13-dihydroxy-7-methoxy-3,5,7,9,11-pentamethyl-2,10-dioxo-oxacyclotetradec-11-en-6-yloxy)-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester

Imidazole-1-carboxylic acid (E)-(2R,3S,7R,9R,10R,11R,13R)-10-((2S,3R,4S,6R)-3-benzoyloxy-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy)-2,3-diethyl-9-methoxy-5,7,9,11,13-pentamethyl-6,12,14-trioxo-oxacyclotetradec-4-en-3-yl ester

C₅₃H₇₇NO₁₄