Bicyclo[2.2.1]hept-5-ene-2-carbohydrazide

Base Information

• Chemical Name: Bicyclo[2.2.1]hept-5-ene-2-carbohydrazide
• CAS No.: 98489-48-6
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.196
• NSC Number: 143636
• DSSTox Substance ID: DTXSID90301472
• Mol file: 98489-48-6.mol

Synonyms:BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOHYDRAZIDE;98489-48-6;Bicyclo[2.2.1]hept-5-ene-2-carboxylicacid, hydrazide;2222492-14-8;NSC143636;DTXSID90301472;110882-66-1;MFCD03014982;AKOS024254581;NSC-143636;CS-0208613;EN300-747035;Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid,hydrazide(9ci)

Chemical Property of Bicyclo[2.2.1]hept-5-ene-2-carbohydrazide

Chemical Property:

• Boiling Point: 339.5±22.0 °C(Predicted)
• PKA: 13.16±0.20(Predicted)
• PSA: 58.61000
• Density: 1.210±0.06 g/cm3(Predicted)
• LogP: 1.72910
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 152.094963011
• Heavy Atom Count: 11
• Complexity: 212

Purity/Quality:

99% ^*data from raw suppliers

bicyclo[2.2.1]hept-5-ene-2-carbohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2CC(C1C=C2)C(=O)NN

Technology Process of Bicyclo[2.2.1]hept-5-ene-2-carbohydrazide

There total 2 articles about Bicyclo[2.2.1]hept-5-ene-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,2S,4S)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester (2903-75-5) → (+/-)-norborn-5-ene-2endo-carboxylic acid hydrazide (98489-48-6,110882-66-1,168912-29-6)

Guidance literature:

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01520a047 DOI:10.1021/ja01155a013

Reference yield:

→ (+/-)-norborn-5-ene-2exo-carboxylic acid hydrazide (98489-48-6,110882-66-1,168912-29-6)

Guidance literature:

/BRN= 3200043/;

DOI:10.1021/ja01520a047

Reference yield:

(+/-)-norborn-5-ene-2endo-carboxylic acid hydrazide (98489-48-6,110882-66-1,168912-29-6) → endo-5-Aminobicyclo[2.2.1]hept-2-ene (18530-45-5,52430-93-0,77697-44-0)

Guidance literature:

With hydrogenchloride; sodium nitrite; Erwaermen des Reaktionsprodukts mit wss.HCl;

DOI:10.1021/ja01155a013

upstream raw materials:

(1S,2S,4S)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester

Downstream raw materials:

endo-5-Aminobicyclo[2.2.1]hept-2-ene