methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate

Base Information

• Chemical Name: methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate
• CAS No.: 119139-47-8
• Molecular Formula: C₂₈H₃₁O₂P
• Molecular Weight: 430.527
• Mol file: 119139-47-8.mol

Synonyms:methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate

Chemical Property of methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate

There total 2 articles about methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl malonate sodium salt (18424-76-5) + methyl chloroformate (79-22-1) + triphenylphosphine (603-35-0) + 1-bromo-2,3-dimethyl-2-butene (5072-70-8) → methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate (119139-47-8)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1246/cl.1988.909

Reference yield:

methyl chloroformate (79-22-1) + (4,5-Dimethyl-hex-4-enyl)-triphenyl-phosphonium; iodide → methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate (119139-47-8)

Guidance literature:

With n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane; Yield given. Multistep reaction; 1.) THF, hexane, 0 deg C, 30 min, 2.) THF, hexane, -78 deg C, 3 h;

DOI:10.1016/0040-4020(96)00608-4

Reference yield: 87.0%

methyl 5,6-dimethyl-2-triphenylphosphoranylidene-5-heptenoate (119139-47-8) + 5-(tert-butyldiphenylsilyl)oxymethyl-1-(p-toluenesulfonyl)-2-indolinole (119139-40-1) → methyl (2Z)-2-<2-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>ethylidene>-5,6-dimethyl-5-heptenoate (119139-41-2) + methyl (2E)-2-<2-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>ethylidene>-5,6-dimethyl-5-heptenoate (119139-41-2)

Guidance literature:

In dichloromethane; for 52h; Yield given; Ambient temperature;

DOI:10.1246/cl.1988.909

upstream raw materials:

dimethyl malonate sodium salt

methyl chloroformate

triphenylphosphine

1-bromo-2,3-dimethyl-2-butene

Downstream raw materials:

methyl (2Z)-2-<2-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>ethylidene>-5,6-dimethyl-5-heptenoate

methyl (2E)-2-<2-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>ethylidene>-5,6-dimethyl-5-heptenoate

4-Azido-3-((E)-3-methoxycarbonyl-6,7-dimethyl-octa-2,6-dienyl)-benzoic acid ethyl ester

(2S)-1-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>-6,7-dimethyl-3-methylene-6-octen-2-ol